Biological Resource Center of Institut Pasteur (CRBIP)

Biological Resource Center of Institut Pasteur (CRBIP)

Research Infrastructure affiliation(s): MIRRI

Location: Paris, France

Website address: www.crbip.pasteur.fr

Local Access Officer: Dr. Chantal Bizet (chantal.bizet@pasteur.fr), dr. Mery Pina (merypi@pasteur.fr)

 

Description

The Biological Resource Centre of Institut Pasteur (CRBIP) maintains a broad diversity of prokaryotic species; strains containing plasmids and genes of interest, strains having particular properties, etc. The CRBIP distributes its biological resources in France and abroad following safety standards for health and the environment in compliance with regulations and laws (Best practices, Nagoya, Protocol, etc.) and ensuring maximum traceability. In addition, it is involved in different research projects focused on bacterial genomics and proteomics, as well as on preservation. The CRBIP is organized to improve the access to microbial material and in particular to bacterial resources, in order to enhance exchange within Europe and non-European countries, to facilitate cross-disciplinary experimental work, to innovate with new better-performing methodologies such as collaborations between private and public laboratories. At the European level, the CRBIP is involved in the MIRRI infrastructure and in the EMBRIC project.

Facilities

The Institut Pasteur boasts high-technology facilities to support world-class research, the development of international projects and the development of transversal actions by making available to its in-house scientists and scientists from other research organisations cutting-edge facilities.

The Institut Pasteur holds its own Biological Resource Centre (CRBIP). It gathers the Collection of Institut Pasteur (CIP: bacteria and plasmids), Pasteur Cyanobacteria Collection (PCC) and the ICAReB biobank. It has globally been certified ISO 9001 version 2000 since 2004 then NF S96-900 since 2009. It has participated in the drafting of the ISO norm in management of culture collections and Biosecurity, and it has also participated in discussions about the establishment of the Nagoya Protocol with the French parliament. Research and technological facilities of the CRBIP include a Next Generation Sequencing platform (using Illumina technology) and a Microflex LT/SH (a compact linear-mode bench-top MALDI-TOF system).

Services

The CRBIP offers services such as preservation (freeze-drying, cryopreservation, etc.), identification and characterization of newly discovered strains, which will, in turn, drive biotechnological research, allowing generating new data to complement the data sets of strains of high relevance for research and development. It also offers access to Next Generation Sequencing (NGS), which is used in order to identify genes and regulatory elements involved in different metabolic processes, providing a wealth of knowledge for comparative biology studies through whole genome sequencing (WGS) of a wide variety of organisms which could serve as a source of novel biomolecules, as well as access to MALDI-TOF mass spectrometry for identification of pure cultures of bacterial strains.

Support offered

TA-users have access to standard disposables and administrative and logistical support and to the services listed above, including troubleshooting with, and basic training in, the use of equipment and technical protocols. Other amenities include an in-house cafeteria, a canteen with a large variety of food and a social space for recreation and networking. The Institut Pasteur does not provide lodging, but it offers advice and assistance for lodging at the International Residence campus of Paris.